Refractory migraine profile in CGRP‐monoclonal antibodies scenario

202145 citationsJournal Articlehybrid Open Access

Authors

Marcello Silvestro · University of Campania "Luigi Vanvitelli"

Alessandro Tessitore · University of Campania "Luigi Vanvitelli"

Fabrizio Scotto di Clemente · University of Campania "Luigi Vanvitelli"

Giorgia Battista · University of Campania "Luigi Vanvitelli"

Gioacchino Tedeschi · University of Campania "Luigi Vanvitelli"

Antonio Russo · University of Campania "Luigi Vanvitelli"

Abstract

We outline that higher frequency of migraine attacks, medication overuse and pain catastrophizing characterize patients with Ref-M not responsive to CGRP-mAbs. In this frame, olanzapine effectiveness on frequency and pain intensity of migraine attacks supports the hypothesis that migraine refractoriness may be subtended by a prominent involvement of the dopaminergic pathway.

Topics & Keywords

Migraine and Headache Studies Sympathectomy and Hyperhidrosis Treatments Trigeminal Neuralgia and Treatments

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Acta Neurologica Scandinavica

Volume 144, Issue 3, pp. 325-333

DOI: 10.1111/ane.13472

Field-Weighted Citation Impact: 6.26