Antibiotic Therapy for 6 or 12 Weeks for Prosthetic Joint Infection

2021207 citationsJournal Articlebronze Open Access

Authors

Louis Bernard · Université de Tours

C. Arvieux · Université de Tours

B. Brunschweiler · Université de Tours

S. Touchais · Université de Tours

Séverine Ansart · Université de Tours

J.P. Bru · Université de Tours

E. Oziol · Université de Tours

Abstract

Among patients with microbiologically confirmed prosthetic joint infections that were managed with standard surgical procedures, antibiotic therapy for 6 weeks was not shown to be noninferior to antibiotic therapy for 12 weeks and resulted in a higher percentage of patients with unfavorable outcomes. (Funded by Programme Hospitalier de Recherche Clinique, French Ministry of Health; DATIPO ClinicalTrials.gov number, NCT01816009.).

Topics & Keywords

Orthopedic Infections and Treatments Orthopaedic implants and arthroplasty Total Knee Arthroplasty Outcomes

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 384, Issue 21, pp. 1991-2001

DOI: 10.1056/nejmoa2020198

Field-Weighted Citation Impact: 29.27