Opening of the Blood–Brain Barrier Using Low-Intensity Pulsed Ultrasound Enhances Responses to Immunotherapy in Preclinical Glioma Models

2021129 citationsJournal Articlebronze Open Access

Authors

Aria Sabbagh · The University of Texas MD Anderson Cancer Center

Kévin Beccaria · Hôpital Necker-Enfants Malades

Xiaoyang Ling · The University of Texas MD Anderson Cancer Center

Anantha Marisetty · The University of Texas MD Anderson Cancer Center

Martina Ott · The University of Texas MD Anderson Cancer Center

Hillary G. Caruso · The University of Texas MD Anderson Cancer Center

Abstract

LIPU increases immune therapeutic delivery to the tumor microenvironment with an associated increase in survival and is an emerging technique for enhancing novel therapies in the brain.

Topics & Keywords

Ultrasound and Hyperthermia Applications Photoacoustic and Ultrasonic Imaging Glioma Diagnosis and Treatment

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Clinical Cancer Research

Volume 27, Issue 15, pp. 4325-4337

DOI: 10.1158/1078-0432.ccr-20-3760

Field-Weighted Citation Impact: 7.81