Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging

2021290 citationsJournal Articlegold Open Access

Authors

Daniel L. McCartney · Edinburgh Cancer Research

Josine L. Min · University of Bristol

Rebecca C. Richmond · University of Bristol

Ake T. Lu · University of California, Los Angeles

Maria Sobczyk · University of Bristol

Gail Davies · University of Edinburgh

Linda Broer ·

Abstract

This study illuminates the genetic architecture underlying epigenetic aging and its shared genetic contributions with lifestyle factors and longevity.

Topics & Keywords

Epigenetics and DNA Methylation Genetic Associations and Epidemiology Genetic Syndromes and Imprinting

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Genome biology

Volume 22, Issue 1, pp. 194-194

DOI: 10.1186/s13059-021-02398-9

Field-Weighted Citation Impact: 16.35