Clinical and Virological Features of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Variants of Concern: A Retrospective Cohort Study Comparing B.1.1.7 (Alpha), B.1.351 (Beta), and B.1.617.2 (Delta)

2021418 citationsJournal Articlebronze Open Access

Authors

Sean Wei Xiang Ong · Tan Tock Seng Hospital

Calvin J. Chiew · Ministry of Health

Li Wei Ang · National Centre for Infectious Diseases

Tze Minn Mak · National Centre for Infectious Diseases

Lin Cui · National Centre for Infectious Diseases

Matthias Paul HS Toh · National University of Singapore

Yi Ding Lim

Abstract

B.1.617.2 was associated with increased severity of illness, and with lower Ct values and longer viral shedding. These findings provide impetus for the rapid implementation of vaccination programs.

Topics & Keywords

SARS-CoV-2 and COVID-19 Research SARS-CoV-2 detection and testing COVID-19 Clinical Research Studies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Clinical Infectious Diseases

Volume 75, Issue 1, pp. e1128-e1136

DOI: 10.1093/cid/ciab721

Field-Weighted Citation Impact: 25.96