The interplay between gray matter and white matter neurodegeneration in subjective cognitive decline

202126 citationsJournal Articlehybrid Open Access

Authors

Nira Cedrés · Stockholm University

Patricia Diaz‐Galvan · Mayo Clinic

Lucio Díaz‐Flores · Hospital Universitario de Canarias

J‐Sebastian Muehlboeck · Karolinska Institutet

Yaiza Molina · Universidad Fernando Pessoa Canarias

José Barroso · Universidad de La Laguna

Eric Westman ·

Abstract

Neurodegeneration processes affecting the GM and WM seem to be associated with each other in SCD and include brain areas other than those typically targeted by Alzheimer's disease. Our findings suggest that SCD may be a sensitive behavioral marker of heterogeneous brain pathologies in individuals recruited from the community.

Topics & Keywords

Dementia and Cognitive Impairment Research Alzheimer's disease research and treatments Functional Brain Connectivity Studies

UN Sustainable Development Goals

Peace, Justice and strong institutions

Publication Details

Published in: Aging

Volume 13, Issue 16, pp. 19963-19977

DOI: 10.18632/aging.203467

Field-Weighted Citation Impact: 2.14