Identifying Immune Cell Infiltration and Effective Diagnostic Biomarkers in Rheumatoid Arthritis by Bioinformatics Analysis

2021117 citationsJournal Articlegold Open Access

Authors

Hongcheng Lu · Jiangsu Province Hospital

Min Xiong · Hubei University of Medicine

Abstract

CCL5, CXCR4, GZMA, and CD8A can be used as diagnostic biomarker for RA. GZMA-Tfh cells, CCL5-M1 macrophages, and CXCR4- memory activated CD4+ T cells/Tfh cells may participate in the occurrence and development of RA, especially GZMA-Tfh cells for the early pathogenesis of RA.

Topics & Keywords

Rheumatoid Arthritis Research and Therapies Systemic Lupus Erythematosus Research Cytokine Signaling Pathways and Interactions

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Frontiers in Immunology

Volume 12, pp. 726747-726747

DOI: 10.3389/fimmu.2021.726747

Field-Weighted Citation Impact: 18.03