Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors

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Authors

Niamh Mullins · Icahn School of Medicine at Mount Sinai

Jooeun Kang · Vanderbilt University Medical Center

Adrián I. Campos · The University of Queensland

Jonathan R. I. Coleman · King's College London

Alexis C. Edwards · Virginia Commonwealth University

Hanga Galfalvy · Columbia University

Daniel F. Levey

Abstract

Our results identify a risk locus that contributes more strongly to SA than other phenotypes and suggest a shared underlying biology between SA and known risk factors that is not mediated by psychiatric disorders.

Topics & Keywords

Suicide and Self-Harm Studies Genetic Neurodegenerative Diseases Cannabis and Cannabinoid Research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Biological Psychiatry

Volume 91, Issue 3, pp. 313-327

DOI: 10.1016/j.biopsych.2021.05.029

Field-Weighted Citation Impact: 24.39