Y chromosomal noncoding RNAs regulate autosomal gene expression via piRNAs in mouse testis

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Authors

Hemakumar M. Reddy · Centre for Cellular and Molecular Biology

Rupa Bhattacharya · Pennington Biomedical Research Center

Shrish Tiwari · Centre for Cellular and Molecular Biology

Kankadeb Mishra · Memorial Sloan Kettering Cancer Center

Pranatharthi Annapurna · Centre for Cellular and Molecular Biology

Zeenath Jehan · Centre for Cellular and Molecular Biology

Nissankararao Mary Praveena

Abstract

Our study elucidates a set of autosomal genes that are potentially regulated by MSYq-derived piRNAs in mouse testis. Sperm phenotypes from the Yq-deleted mice seem to be similar to that reported in inter-specific male-sterile hybrids. Taken together, this study provides novel insights into possible role of MSYq-derived ncRNAs in male sterility and speciation.

Topics & Keywords

Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities Chromosomal and Genetic Variations RNA Research and Splicing

Publication Details

Published in: BMC Biology

Volume 19, Issue 1, pp. 198-198

DOI: 10.1186/s12915-021-01125-x

Field-Weighted Citation Impact: 1.21

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Y chromosomal noncoding RNAs regulate autosomal gene expression via piRNAs in mouse testis

Authors

Abstract

Topics & Keywords

Publication Details