Hepatectomy Followed by mFOLFOX6 Versus Hepatectomy Alone for Liver-Only Metastatic Colorectal Cancer (JCOG0603): A Phase II or III Randomized Controlled Trial

2021210 citationsJournal Article

Authors

Yukihide Kanemitsu · Tokyo National Hospital

Yasuhiro Shimizu · Aichi Cancer Center

Junki Mizusawa · Tokyo National Hospital

Yoshitaka Inaba · Aichi Cancer Center

Tetsuya Hamaguchi · Saitama Medical University

Dai Shida · Tokyo National Hospital

Masayuki Ohue · Osaka International Cancer Institute

Koji Komori

Abstract

DFS did not correlate with OS for liver-only metastatic CRC. Adjuvant chemotherapy with mFOLFOX6 improves DFS among patients treated with hepatectomy for CRC liver metastasis. It remains unclear whether chemotherapy improves OS.

Topics & Keywords

Hepatocellular Carcinoma Treatment and Prognosis Colorectal Cancer Treatments and Studies Intraperitoneal and Appendiceal Malignancies

Publication Details

Published in: Journal of Clinical Oncology

Volume 39, Issue 34, pp. 3789-3799

DOI: 10.1200/jco.21.01032

Field-Weighted Citation Impact: 17.87

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Hepatectomy Followed by mFOLFOX6 Versus Hepatectomy Alone for Liver-Only Metastatic Colorectal Cancer (JCOG0603): A Phase II or III Randomized Controlled Trial

Authors

Abstract

Topics & Keywords

Publication Details