A Guideline for Reporting Mediation Analyses of Randomized Trials and Observational Studies

2021484 citationsJournal Articlehybrid Open Access

Authors

Hopin Lee · Nuffield Orthopaedic Centre

Aidan G Cashin · UNSW Sydney

Sarah E Lamb · University of Exeter

Sally Hopewell · Nuffield Orthopaedic Centre

Stijn Vansteelandt · Ghent University

Tyler J. VanderWeele · Harvard University

David P. MacKinnon ·

Abstract

The AGReMA statement provides recommendations for reporting primary and secondary mediation analyses of randomized trials and observational studies. Improved reporting of studies that use mediation analyses could facilitate peer review and help produce publications that are complete, accurate, transparent, and reproducible.

Topics & Keywords

Advanced Causal Inference Techniques Statistical Methods in Clinical Trials Health Systems, Economic Evaluations, Quality of Life

UN Sustainable Development Goals

Partnerships for the goals

Publication Details

Published in: JAMA

Volume 326, Issue 11, pp. 1045-1045

DOI: 10.1001/jama.2021.14075

Field-Weighted Citation Impact: 76.79