Epigenetic Age and the Risk of Incident Atrial Fibrillation

2021113 citationsJournal Articlebronze Open Access

Authors

Jason D. Roberts · Western University

Eric Vittinghoff · University of California, San Francisco

Ake T. Lu · University of California, Los Angeles

Alvaro Alonso · Emory University

Biqi Wang · Faculty of Public Health

Colleen M. Sitlani · University of Washington

Pedrum Mohammadi-Shemirani · McMaster University Medical Centre

Myriam Fornage

Abstract

Our study identified adjusted associations between EAA measures and incident AF, suggesting that biological aging plays an important role independent of chronological age, though a potential underlying causal relationship remains unclear. These aging processes may be modifiable and not constrained by the immutable factor of time.

Topics & Keywords

Epigenetics and DNA Methylation Genetic Associations and Epidemiology Health, Environment, Cognitive Aging

Publication Details

Published in: Circulation

Volume 144, Issue 24, pp. 1899-1911

DOI: 10.1161/circulationaha.121.056456

Field-Weighted Citation Impact: 5.68

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Epigenetic Age and the Risk of Incident Atrial Fibrillation

Authors

Abstract

Topics & Keywords

Publication Details