Combining Blood Gene Expression and Cellfree DNA to Diagnose Subclinical Rejection in Kidney Transplant Recipients

202177 citationsJournal Articlegreen Open Access

Authors

Sookhyeon Park · Northwestern University

Kexin Guo · Northwestern University

Raymond L. Heilman · Northwestern University

Emilio D. Poggio · Northwestern University

David J. Taber · Northwestern University

Christopher L. Marsh · Northwestern University

Sunil M. Kurian ·

Abstract

A combination of blood-based biomarkers can improve detection and provide less invasive monitoring for subclinical rejection. In this study, the gene expression profile detected more cellular rejection, whereas donor-derived cfDNA detected more antibody-mediated rejection.

Topics & Keywords

Renal Transplantation Outcomes and Treatments Transplantation: Methods and Outcomes Organ Transplantation Techniques and Outcomes

Publication Details

Published in: Clinical Journal of the American Society of Nephrology

Volume 16, Issue 10, pp. 1539-1551

DOI: 10.2215/cjn.05530421

Field-Weighted Citation Impact: 10.22

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Combining Blood Gene Expression and Cellfree DNA to Diagnose Subclinical Rejection in Kidney Transplant Recipients

Authors

Abstract

Topics & Keywords

Publication Details