Relationship between the Plasma Proteome and Changes in Inflammatory Markers after Bariatric Surgery

202136 citationsJournal Articlegold Open Access

Authors

Helene Fachim · University of Manchester

Zohaib Iqbal · University of Manchester

Martin Gibson · University of Manchester

Ivona Baričević-Jones · University of Manchester

A. Campbell · Manchester Academic Health Science Centre

Bethany Geary · University of Manchester

Akheel A. Syed ·

Abstract

Using SWATH-MS, we identified several proteins that are involved in the inflammatory response whose levels change in patients who achieve remission of T2DM after bariatric surgery in tandem with changes in IL6, TNFα and/or CRP. Future studies are needed to clarify the underlying mechanisms in how MBS decreases low-grade inflammation.

Topics & Keywords

Adipokines, Inflammation, and Metabolic Diseases Cardiovascular Disease and Adiposity Adipose Tissue and Metabolism

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Cells

Volume 10, Issue 10, pp. 2798-2798

DOI: 10.3390/cells10102798

Field-Weighted Citation Impact: 4.52