Gut–microbiota–microglia–brain interactions in Alzheimer’s disease: knowledge-based, multi-dimensional characterization

202131 citationsJournal Articlegold Open Access

Authors

QuanQiu Wang · Case Western Reserve University

Pamela B. Davis · Case Western Reserve University

Xin Qi · Case Western Reserve University

Shu G. Chen · Case Western Reserve University

Mark E. Gurney · Tetra Therapeutics (United States)

George Perry · The University of Texas at San Antonio

P. Murali Doraiswamy

Abstract

Our analysis produces a novel framework to offer insights into the mechanistic links between gut microbial metabolites, microglia, and AD, with the overall goal to facilitate disease mechanism understanding, therapeutic target identification, and designing confirmatory experimental studies.

Topics & Keywords

Gut microbiota and health Bioinformatics and Genomic Networks Diet and metabolism studies

Publication Details

Published in: Alzheimer s Research & Therapy

Volume 13, Issue 1, pp. 177-177

DOI: 10.1186/s13195-021-00917-1

Field-Weighted Citation Impact: 1.87

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Gut–microbiota–microglia–brain interactions in Alzheimer’s disease: knowledge-based, multi-dimensional characterization

Authors

Abstract

Topics & Keywords

Publication Details