Aged neutrophils form mitochondria-dependent vital NETs to promote breast cancer lung metastasis

2021163 citationsJournal Articlegold Open Access

Authors

Chenghui Yang · Wenzhou Medical University

Zhen Wang · Second Affiliated Hospital of Zhejiang University

Lili Li · Second Affiliated Hospital of Zhejiang University

Zhigang Zhang · Second Affiliated Hospital of Zhejiang University

Xiaoyan Jin · Taizhou Municipal Hospital

Pin Wu · Second Affiliated Hospital of Zhejiang University

Shanshan Sun

Abstract

Naged exerts a vital role in breast cancer lung metastasis, and strategies targeting SIRT1-Naged-NETs axis show promise for translational application.

Topics & Keywords

Immune cells in cancer Neutrophil, Myeloperoxidase and Oxidative Mechanisms Nanoplatforms for cancer theranostics

UN Sustainable Development Goals

Life below water

Publication Details

Published in: Journal for ImmunoTherapy of Cancer

Volume 9, Issue 10, pp. e002875-e002875

DOI: 10.1136/jitc-2021-002875

Field-Weighted Citation Impact: 8.11