Association between senescence of T cells and disease activity in patients with systemic lupus erythematosus

202125 citationsJournal Articlediamond Open Access

Authors

Handono Kalim · RSUD Prof. Dr. Saiful Anwar Malang

Cesarius Singgih Wahono · University of Brawijaya

Bunga Petriana Oktarini Permana · University of Brawijaya

Mirza Zaka Pratama · RSUD Prof. Dr. Saiful Anwar Malang

Kusworini Handono · University of Brawijaya

Abstract

Systemic lupus erythematosus patients showed significantly higher senescence T cell markers compared to controls, and the increase of T cell senescence, especially in the CD8 compartment, has some association with increased disease activity in patients with SLE.

Topics & Keywords

Systemic Lupus Erythematosus Research Atherosclerosis and Cardiovascular Diseases T-cell and B-cell Immunology

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Reumatologia/Rheumatology

Volume 59, Issue 5, pp. 292-301

DOI: 10.5114/reum.2021.110318

Field-Weighted Citation Impact: 2.21