<scp>miR</scp>‐146b Protects the Perinatal Brain against Microglia‐Induced Hypomyelination

202131 citationsJournal Articlehybrid Open Access

Authors

Cindy Bokobza · NeuroDiderot

Pooja Joshi · Université Paris Cité

Anne‐Laure Schang · Inserm

Zsolt Csaba · NeuroDiderot

Valérie Faivre · NeuroDiderot

Amélie Montané · NeuroDiderot

Anne Galland · NeuroDiderot

Abstract

These findings support that miRNA-146b-5p is a major regulator of microglia phenotype and could be targeted to reduce the incidence and the severity of perinatal brain injuries and their long-term consequences. ANN NEUROL 2022;91:48-65.

Topics & Keywords

MicroRNA in disease regulation Neonatal and fetal brain pathology Neurogenesis and neuroplasticity mechanisms

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Annals of Neurology

Volume 91, Issue 1, pp. 48-65

DOI: 10.1002/ana.26263

Field-Weighted Citation Impact: 2.17