IL‐6–induced cGGNBP2 encodes a protein to promote cell growth and metastasis in intrahepatic cholangiocarcinoma

2021133 citationsJournal Articlehybrid Open Access

Authors

Hui Li · Chongqing University

Tian Lan · West China Hospital of Sichuan University

Hailing Liu · West China Hospital of Sichuan University

Chang Liu · Sichuan University

Junlong Dai · West China Hospital of Sichuan University

Lin Xu · Sichuan University

Yunshi Cai ·

Abstract

Our study demonstrates that cGGNBP2-184aa, a protein encoded by IL-6-induced cGGNBP2, formed a positive feedback loop to facilitate ICC progression and may serve as an auxiliary target for clinical IL-6/STAT3-targeting treatments in ICC.

Topics & Keywords

Circular RNAs in diseases Cancer-related molecular mechanisms research MicroRNA in disease regulation

Publication Details

Published in: Hepatology

Volume 75, Issue 6, pp. 1402-1419

DOI: 10.1002/hep.32232

Field-Weighted Citation Impact: 8.78

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IL‐6–induced cGGNBP2 encodes a protein to promote cell growth and metastasis in intrahepatic cholangiocarcinoma

Authors

Abstract

Topics & Keywords

Publication Details