Analysis of the immune landscape in virus-induced cancers using a novel integrative mechanism discovery approach

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Authors

Lindsay M. Wong · University of California San Diego

Wei Tse Li · University of California San Diego

Neil Shende · University of California San Diego

Joseph C. Tsai · University of California San Diego

Jiayan Ma · University of California San Diego

Jaideep Chakladar · University of California San Diego

Aditi Gnanasekar

Abstract

Our study offers a new approach to mechanism identification through integrating functional annotations and large-scale sequencing data, which may be invaluable to the discovery of new immunotherapy targets for virus-induced cancers.

Topics & Keywords

RNA modifications and cancer Viral-associated cancers and disorders Cancer-related molecular mechanisms research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Computational and Structural Biotechnology Journal

Volume 19, pp. 6240-6254

DOI: 10.1016/j.csbj.2021.11.013

Field-Weighted Citation Impact: 0.24