Abstract 14411: Predictors of Delirium Among Hospitalized Older Adults With Cardiovascular Disease

Introduction: Delirium is an acute confusional state typically seen in patients admitted to the hospital that can affect mentation, cause agitation, and complicate inpatient stays. The number of older adults with cardiovascular diseases is rapidly increasing. When admitted to the hospital, the elderly are at increased risk of developing delirium. Hypothesis: We hypothesized that there will be predictors that are associated with delirium among older adults who were hospitalized in acute care units with cardiovascular disease. Methods: A retrospective chart review was conducted on patients initially admitted to the coronary care unit (CCU) and cardiac intermediate care unit (CIMU) of a major metropolitan hospital between January 2019 and December 2019. Patients under the age of 65 were excluded. The remaining patients were analyzed with logistic multivariable regression and odds ratios were calculated for factors associated with developing delirium, adjusting for patient characteristics including Charlson’s Comorbidity Index (CCI) and admission reasons. Results: A total of 327 patients with a mean age of 75.6 years were analyzed. Of those patients, 227 (69.4%) had a CCI score of 4 or less. There were no significant associations with development of delirium at any CCI score compared to a score of 0; however, certain admission reasons were significantly associated with delirium, including needing a coronary artery bypass graft and minimally invasive valve repair (Table 1). Conclusions: Several different admission diagnoses were significantly associated with increased odds of delirium. Although CCI scores were not significantly associated with the development of delirium during the hospitalization, other risk factors such as age, reason for admission, and procedures performed may have stronger associations. The current study will be a foundation to develop a more patient-centered strategy to prevent and manage delirium in the growing elderly population.