Magnetic Resonance Imaging Characteristics of Molecular Subgroups in Pediatric H3 K27M Mutant Diffuse Midline Glioma

202117 citationsJournal Articlehybrid Open Access

Authors

Annika Hohm · Universität Hamburg

Michael Karremann · Heidelberg University

Gerrit H. Gielen · University Hospital Bonn

Torsten Pietsch · University Hospital Bonn

Monika Warmuth‐Metz · Universitätsklinikum Würzburg

Lindsey A. Vandergrift · Harvard University

Brigitte Bison ·

Abstract

With this study, we are the first to provide detailed MR imaging data on H3 K27M mutant pDMG with respect to molecular subgroup status in a large patient cohort. Our findings may support diagnosis and future targeted therapeutic trials of pDMG within the framework of the radiogenomics concept.

Topics & Keywords

Glioma Diagnosis and Treatment Meningioma and schwannoma management Neuroblastoma Research and Treatments

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Clinical Neuroradiology

Volume 32, Issue 1, pp. 249-258

DOI: 10.1007/s00062-021-01120-3

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