International Study of Intracranial Aneurysm Treatment Using Woven EndoBridge: Results of the WorldWideWEB Consortium

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Authors

Adam A. Dmytriw · Brigham and Women's Hospital

Jose Danilo Bengzon Diestro · St. Michael's Hospital

Mahmoud Dibas · Massachusetts General Hospital

Kevin Phan · Massachusetts General Hospital

Ahmad Sweid · Thomas Jefferson University

Hugo Cuellar · Louisiana State University in Shreveport

Sovann V. Lay

Abstract

HomeStrokeVol. 53, No. 2International Study of Intracranial Aneurysm Treatment Using Woven EndoBridge: Results of the WorldWideWEB Consortium Free AccessLetterPDF/EPUBAboutView PDFView EPUBSections ToolsAdd to favoritesDownload citationsTrack citationsPermissionsDownload Articles + Supplements ShareShare onFacebookTwitterLinked InMendeleyRedditDiggEmail Jump toSupplementary MaterialsFree AccessLetterPDF/EPUBInternational Study of Intracranial Aneurysm Treatment Using Woven EndoBridge: Results of the WorldWideWEB Consortium Adam A. Dmytriw, MD, MPH, MSc, Jose Danilo Bengzon Diestro, MD, Mahmoud Dibas, MD, Kevin Phan, MD, MSc, MPhil, Ahmad Sweid, MD, Hugo H. Cuellar-Saenz, MD, Sovann V. Lay, MD, Adrien Guenego, MD, Leonardo Renieri, MD, Ali Al Balushi, MD, Sri Hari Sundararajan, MD, Joseph Carnevale, MD, Guillaume Saliou, MD, PhD, Markus Möhlenbruch, MD, Justin E. Vranic, MD, Pablo Harker, MD, James D. Rabinov, MD, Ivan Lylyk, MD, Paul M. Foreman, MD, Jay A. Vachhani, MD, Vedran Župančić, MD, Muhammad U. Hafeez, MD, Caleb Rutledge, MD, Muhammad Waqas, MBBS, Vincent M. Tutino, PhD, Rawad Abbas, MD, Yasuaki Inoue, MD, Carolina Capirossi, MD, Yifan Ren, MD, Clemens M. Schirmer, MD, PhD, Mariangela Piano, MD, Anna Luisa Kühn, MD, PhD, Caterina Michelozzi, MD, Stéphanie Elens, MD, Robert W. Regenhardt, MD, PhD, Sherief Ghozy, MD, Naif M. Alotaibi, MD, MSc, Stavropoula Tjoumakaris, MD, Robert M. Starke, MD, Boris Lubicz, MD, PhD, Pietro Panni, MD, Ajit S. Puri, MD, Guglielmo Pero, MD, Christoph J. Griessenauer, MD, Christian Ulfert, MD, Hamed Asadi, MD, PhD, Mark Brooks, MBBS, Julian Maingard, MBBS, Ashu Jhamb, MBBS, Adnan Siddiqui, MD, Andrew F. Ducruet, MD, Felipe C. Albuquerque, MD, Peter Kan, MD, Vladimir Kalousek, MD, Pedro Lylyk, MD, Amey Savardekar, MD, Srikanth Boddu, MD, MSc, Jared Knopman, MD, Nicola Limbucci, MD, Karen S. Chen, MD, MPhil, Mohammad A. Aziz-Sultan, MD, Christopher J. Stapleton, MD, Pascal Jabbour, MD, Christophe Cognard, MD, Aman B. Patel, MD and Nimer Adeeb, MD Adam A. DmytriwAdam A. Dmytriw Correspondence to: Adam A. Dmytriw, MD, MPH, MSc, Neuroendovascular Program, Massachusetts General Hospital, Harvard Medical School, 55 Fruit St, Boston, MA 02114. Email E-mail Address: [email protected] Neuroendovascular Program, Massachusetts General Hospital, Harvard University, Boston (A.A.D., M.D., J.E.V., J.D.R., S.G., N.M.A., P.H., A.B.P.). Neuroradiology & Neurosurgery Services, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (A.A.D., Y.I., K.S.C., M.A.A.-S.). , Jose Danilo Bengzon DiestroJose Danilo Bengzon Diestro https://orcid.org/0000-0001-8450-2021 Division of Diagnostic and Therapeutic Neuroradiology, Department of Medical Imaging, St. Michael's Hospital, Toronto, ON, Canada (J.D.B.D., R.A., S.T., P.J.). , Mahmoud DibasMahmoud Dibas Neuroendovascular Program, Massachusetts General Hospital, Harvard University, Boston (A.A.D., M.D., J.E.V., J.D.R., S.G., N.M.A., P.H., A.B.P.). , Kevin PhanKevin Phan https://orcid.org/0000-0002-5940-3555 Neuroendovascular Program, Massachusetts General Hospital, Harvard University, Boston (A.A.D., M.D., J.E.V., J.D.R., S.G., N.M.A., P.H., A.B.P.). , Ahmad SweidAhmad Sweid Department of Neurosurgery, Thomas Jefferson University, Philadelphia, PA (A. Sweid, A. Savardekar, N.A.). , Hugo H. Cuellar-SaenzHugo H. Cuellar-Saenz Departments of Neurosurgery and Interventional Neuroradiology, Louisiana State University, Shreveport (H.H.C.-S., C. Cognard). , Sovann V. LaySovann V. Lay https://orcid.org/0000-0003-4105-0664 Service de Neuroradiologie Diagnostique et Thérapeutique, Centre Hospitalier de Toulouse, Hôpital Purpan, France (S.V.L., A.G., S.E., B.L.). , Adrien GuenegoAdrien Guenego Service de Neuroradiologie Diagnostique et Thérapeutique, Centre Hospitalier de Toulouse, Hôpital Purpan, France (S.V.L., A.G., S.E., B.L.). Service de Neuroradiologie Interventionnelle, Hôpital Universitaire Erasme, Bruxelles Belgique (A.G., C. Capirossi, N.L.). , Leonardo RenieriLeonardo Renieri Interventistica Neurovascolare, Ospedale Careggi di Firenze, Florence, Italy (L.R., S.B., J.K.). , Ali Al BalushiAli Al Balushi Neurosurgery & Interventional Neuroradiology, New York Presbyterian Hospital, Weill Cornell School of Medicine, NY (A.A.B., S.H.S., J.C.). , Sri Hari SundararajanSri Hari Sundararajan https://orcid.org/0000-0002-6017-3603 Neurosurgery & Interventional Neuroradiology, New York Presbyterian Hospital, Weill Cornell School of Medicine, NY (A.A.B., S.H.S., J.C.). , Joseph CarnevaleJoseph Carnevale https://orcid.org/0000-0002-9477-9996 Neurosurgery & Interventional Neuroradiology, New York Presbyterian Hospital, Weill Cornell School of Medicine, NY (A.A.B., S.H.S., J.C.). , Guillaume SaliouGuillaume Saliou https://orcid.org/0000-0003-3832-7976 Service de Radiodiagnostic et Radiologie Interventionnelle, Centre Hospitalier Vaudois de Lausanne, Switzerland (G.S.). , Markus MöhlenbruchMarkus Möhlenbruch Sektion Vaskuläre und Interventionelle Neuroradiologie, Universitätsklinikum Heidelberg, Germany (M.M., C.U., R.W.R., C.J.S.). , Justin E. VranicJustin E. Vranic Neuroendovascular Program, Massachusetts General Hospital, Harvard University, Boston (A.A.D., M.D., J.E.V., J.D.R., S.G., N.M.A., P.H., A.B.P.). , Pablo HarkerPablo Harker Neuroendovascular Program, Massachusetts General Hospital, Harvard University, Boston (A.A.D., M.D., J.E.V., J.D.R., S.G., N.M.A., P.H., A.B.P.). , James D. RabinovJames D. Rabinov Neuroendovascular Program, Massachusetts General Hospital, Harvard University, Boston (A.A.D., M.D., J.E.V., J.D.R., S.G., N.M.A., P.H., A.B.P.). , Ivan LylykIvan Lylyk https://orcid.org/0000-0002-6048-4225 Equipo de Neurocirugía Endovascular y Radiología Intervencionista, Clínica La Sagrada Familia, Buenos Aires, Argentina (I.L., J.A.V., P.L.). , Paul M. ForemanPaul M. Foreman https://orcid.org/0000-0001-8743-5119 Neurosurgery Group, Orlando Health Neuroscience and Rehabilitation Institute, Orlando, FL (P.M.F.). , Jay A. VachhaniJay A. Vachhani https://orcid.org/0000-0002-2446-4315 Equipo de Neurocirugía Endovascular y Radiología Intervencionista, Clínica La Sagrada Familia, Buenos Aires, Argentina (I.L., J.A.V., P.L.). , Vedran ŽupančićVedran Župančić https://orcid.org/0000-0002-1495-4345 Subdivision of Interventional Neuroradiology, Department of Radiology, Clinical Hospital Center 'Sisters of Mercy', Zagreb, Croatia (V.Ž., V.K.). , Muhammad U. HafeezMuhammad U. Hafeez https://orcid.org/0000-0001-8631-4227 Department of Neurosurgery, UTMB and Baylor School of Medicine, Houston, TX (M.U.H., F.C.A., P.K.). , Caleb RutledgeCaleb Rutledge Department of Neurosurgery, Barrow Neurological Institute, Phoenix, AZ (C.R., A.F.D.). , Muhammad WaqasMuhammad Waqas Department of Neurosurgery, State University of New York at Buffalo (M.W., V.M.T., A. Siddiqui). , Vincent M. TutinoVincent M. Tutino https://orcid.org/0000-0002-1331-2551 Department of Neurosurgery, State University of New York at Buffalo (M.W., V.M.T., A. Siddiqui). , Rawad AbbasRawad Abbas https://orcid.org/0000-0001-9820-5781 Division of Diagnostic and Therapeutic Neuroradiology, Department of Medical Imaging, St. Michael's Hospital, Toronto, ON, Canada (J.D.B.D., R.A., S.T., P.J.). , Yasuaki InoueYasuaki Inoue https://orcid.org/0000-0003-1855-5891 Neuroradiology & Neurosurgery Services, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (A.A.D., Y.I., K.S.C., M.A.A.-S.). , Carolina CapirossiCarolina Capirossi https://orcid.org/0000-0001-5637-2266 Service de Neuroradiologie Interventionnelle, Hôpital Universitaire Erasme, Bruxelles Belgique (A.G., C. Capirossi, N.L.). , Yifan RenYifan Ren https://orcid.org/0000-0001-6518-6828 Neurointerventional Services, Department of Radiology, Austin Health, Melbourne, Victoria, Australia (Y.R., H.A., M.B., J.M., A.J.). , Clemens M. SchirmerClemens M. Schirmer Department of Neurosurgery and Radiology, Geisinger Hospital, Danville, PA (C.M.S., C.J.G.). Research Institute of Neurointervention, Paracelsus Medical University, Salzburg, Austria (C.M.S., C.J.G.). , Mariangela PianoMariangela Piano https://orcid.org/0000-0003-0470-1202 Interventistica Neurovascolare, Ospedale Niguarda Cà Granda, Milano, Italy (M.P., G.P.). , Anna Luisa KühnAnna Luisa Kühn Department of Neurointerventional Radiology, UMass Memorial Hospital, Worcester, MA (A.L.K., A.S.P.). , Caterina MichelozziCaterina Michelozzi https://orcid.org/0000-0001-6339-448X Interventistica Neurovascolare, Ospedale San Raffaele Milano, Italy (C.M., P.P.). , Stéphanie ElensStéphanie Elens Service de Neuroradiologie Diagnostique et Thérapeutique, Centre Hospitalier de Toulouse, Hôpital Purpan, France (S.V.L., A.G., S.E., B.L.). , Robert W. RegenhardtRobert W. Regenhardt Sektion Vaskuläre und Interventionelle Neuroradiologie, Universitätsklinikum Heidelberg, Germany (M.M., C.U., R.W.R., C.J.S.). , Sherief GhozySherief Ghozy https://orcid.org/0000-0001-5629-3023 Neuroendovascular Program, Massachusetts General Hospital, Harvard University, Boston (A.A.D., M.D., J.E.V., J.D.R., S.G., N.M.A., P.H., A.B.P.). , Naif M. AlotaibiNaif M. Alotaibi Neuroendovascular Program, Massachusetts General Hospital, Harvard University, Boston (A.A.D., M.D., J.E.V., J.D.R., S.G., N.M.A., P.H., A.B.P.). , Stavropoula TjoumakarisStavropoula Tjoumakaris Division of Diagnostic and Therapeutic Neuroradiology, Department of Medical Imaging, St. Michael's Hospital, Toronto, ON, Canada (J.D.B.D., R.A., S.T., P.J.). , Robert M. StarkeRobert M. Starke Deparment of Neurosurgery, University of Miami, FL (R.M.S.). , Boris LubiczBoris Lubicz https://orcid.org/0000-0001-8312-2115 Service de Neuroradiologie Diagnostique et Thérapeutique, Centre Hospitalier de Toulouse, Hôpital Purpan, France (S.V.L., A.G., S.E., B.L.). , Pietro PanniPietro Panni https://orcid.org/0000-0001-8109-9118 Interventistica Neurovascolare, Ospedale San Raffaele Milano, Italy (C.M., P.P.). , Ajit S. PuriAjit S. Puri Department of Neurointerventional Radiology, UMass Memorial Hospital, Worcester, MA (A.L.K., A.S.P.). , Guglielmo PeroGuglielmo Pero https://orcid.org/0000-0002-8932-6909 Interventistica Neurovascolare, Ospedale Niguarda Cà Granda, Milano, Italy (M.P., G.P.). , Christoph J. GriessenauerChristoph J. Griessenauer Department of Neurosurgery and Radiology, Geisinger Hospital, Danville, PA (C.M.S., C.J.G.). Research Institute of Neurointervention, Paracelsus Medical University, Salzburg, Austria (C.M.S., C.J.G.). , Christian UlfertChristian Ulfert Sektion Vaskuläre und Interventionelle Neuroradiologie, Universitätsklinikum Heidelberg, Germany (M.M., C.U., R.W.R., C.J.S.). , Hamed AsadiHamed Asadi https://orcid.org/0000-0003-2475-9727 Neurointerventional Services, Department of Radiology, Austin Health, Melbourne, Victoria, Australia (Y.R., H.A., M.B., J.M., A.J.). , Mark BrooksMark Brooks https://orcid.org/0000-0001-5034-570X Neurointerventional Services, Department of Radiology, Austin Health, Melbourne, Victoria, Australia (Y.R., H.A., M.B., J.M., A.J.). , Julian MaingardJulian Maingard Neurointerventional Services, Department of Radiology, Austin Health, Melbourne, Victoria, Australia (Y.R., H.A., M.B., J.M., A.J.). , Ashu JhambAshu Jhamb https://orcid.org/0000-0002-7097-1641 Neurointerventional Services, Department of Radiology, Austin Health, Melbourne, Victoria, Australia (Y.R., H.A., M.B., J.M., A.J.). , Adnan SiddiquiAdnan Siddiqui Department of Neurosurgery, State University of New York at Buffalo (M.W., V.M.T., A. Siddiqui). , Andrew F. DucruetAndrew F. Ducruet Department of Neurosurgery, Barrow Neurological Institute, Phoenix, AZ (C.R., A.F.D.). , Felipe C. AlbuquerqueFelipe C. Albuquerque Department of Neurosurgery, UTMB and Baylor School of Medicine, Houston, TX (M.U.H., F.C.A., P.K.). , Peter KanPeter Kan Department of Neurosurgery, UTMB and Baylor School of Medicine, Houston, TX (M.U.H., F.C.A., P.K.). , Vladimir KalousekVladimir Kalousek https://orcid.org/0000-0002-1439-0930 Subdivision of Interventional Neuroradiology, Department of Radiology, Clinical Hospital Center 'Sisters of Mercy', Zagreb, Croatia (V.Ž., V.K.). , Pedro LylykPedro Lylyk Equipo de Neurocirugía Endovascular y Radiología Intervencionista, Clínica La Sagrada Familia, Buenos Aires, Argentina (I.L., J.A.V., P.L.). , Amey SavardekarAmey Savardekar https://orcid.org/0000-0002-9305-7457 Department of Neurosurgery, Thomas Jefferson University, Philadelphia, PA (A. Sweid, A. Savardekar, N.A.). , Srikanth BodduSrikanth Boddu Interventistica Neurovascolare, Ospedale Careggi di Firenze, Florence, Italy (L.R., S.B., J.K.). , Jared KnopmanJared Knopman https://orcid.org/0000-0001-5871-5517 Interventistica Neurovascolare, Ospedale Careggi di Firenze, Florence, Italy (L.R., S.B., J.K.). , Nicola LimbucciNicola Limbucci Service de Neuroradiologie Interventionnelle, Hôpital Universitaire Erasme, Bruxelles Belgique (A.G., C. Capirossi, N.L.). , Karen S. ChenKaren S. Chen https://orcid.org/0000-0002-5034-3867 Neuroradiology & Neurosurgery Services, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (A.A.D., Y.I., K.S.C., M.A.A.-S.). , Mohammad A. Aziz-SultanMohammad A. Aziz-Sultan Neuroradiology & Neurosurgery Services, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (A.A.D., Y.I., K.S.C., M.A.A.-S.). , Christopher J. StapletonChristopher J. Stapleton Neuroendovascular Program, Massachusetts General Hospital, Harvard University, Boston (A.A.D., M.D., J.E.V., J.D.R., S.G., N.M.A., P.H., A.B.P.). , Pascal JabbourPascal Jabbour Division of Diagnostic and Therapeutic Neuroradiology, Department of Medical Imaging, St. Michael's Hospital, Toronto, ON, Canada (J.D.B.D., R.A., S.T., P.J.). , Christophe CognardChristophe Cognard Departments of Neurosurgery and Interventional Neuroradiology, Louisiana State University, Shreveport (H.H.C.-S., C. Cognard). , Aman B. PatelAman B. Patel Neuroendovascular Program, Massachusetts General Hospital, Harvard University, Boston (A.A.D., M.D., J.E.V., J.D.R., S.G., N.M.A., P.H., A.B.P.). and Nimer AdeebNimer Adeeb Department of Neurosurgery, Thomas Jefferson University, Philadelphia, PA (A. Sweid, A. Savardekar, N.A.). Originally published17 Dec 2021https://doi.org/10.1161/STROKEAHA.121.037609Stroke. 2022;53:e47–e49is corrected byCorrection to: International Study of Intracranial Aneurysm Treatment Using Woven EndoBridge: Results of the WorldWideWEB ConsortiumOther version(s) of this articleYou are viewing the most recent version of this article. Previous versions: December 17, 2021: Ahead of Print Endovascular treatment of wide-neck bifurcation aneurysms is notoriously challenging, as wide necks predispose to coil herniation into the parent artery and the bifurcation location poses challenges to use of assist devices. While flow diversion has revolutionized the treatment of wide-necked sidewall aneurysms, tubular flow diverting stents for bifurcation aneurysms are often unable to cover the entire length of the aneurysm neck and preclude further attempts at coiling.The Woven EndoBridge device (WEB) was designed specifically for wide-neck bifurcation aneurysms. This study aims to present multi-center data that can aid clinicians in decision-making and prognostication when considering the use of a WEB device.MethodsThe data that support the findings of this study are available from the corresponding author upon reasonable request. The primary Institutional Review Board approval was from the lead institution. Individual approval was obtained at all centers included in the consortium. A retrospective review of prospectively maintained databases at 22 academic institutions was performed to identify adult patients with intracranial aneurysms treated with the WEB device. Both ruptured and unruptured aneurysms in all intracranial locations (including bifurcation and sidewall aneurysms) were included. For more details, see Methods in the Supplemental Material.Angiographic outcome was assessed using digital subtraction angiography, magnetic resonance angiography, or computed tomography angiography. Aneurysm occlusion after treatment, both immediately and at last follow-up, were categorized using the validated WEB occlusion 3-point scale: complete occlusion, neck remnant, and aneurysm remnant. Adequate occlusion was defined as either complete occlusion or neck remnant with lack of aneurysm remnant. WEB device compaction refers to device shape modification and is defined as the percentage reduction in the distance between the 2 WEB markers (distal and proximal) between the initial procedure digital subtraction angiography and imaging at the last follow-up.ResultsThe cumulative population comprised 671 patients (median age 61.4 years; 71.2% female) with 683 intracranial aneurysms. Middle cerebral artery bifurcation (30.2%) was the most common location. Previously ruptured aneurysms accounted for 26.2% of all aneurysms, of which 23.9% were acute (<2 weeks). At the last follow-up (median 11 months), adequate occlusion was documented in 85.7% of aneurysms and complete occlusion was at 57.8%. Retreatment was required in 7.8% of aneurysms. Thromboembolic complications were encountered in 7.5% of procedures, of which only 4.0% were symptomatic and 2.0% were permanent. Hemorrhagic complications were encountered in 3.0% of procedures. No patient experienced aneurysm re-rupture after treatment. Deployment issues were encountered in 1.8% of patients.Minor compaction (adjusted odds ratio, 0.45 [95% CI, 0.24–0.86], P=0.015) or major compaction (adjusted odds ratio, 0.25 [95% CI, 0.11–0.57], P=0.001) as compared with no compaction were significantly associated with lower rates of adequate aneurysm occlusion. Furthermore, compared with those who had complete occlusion, immediate remnant aneurysm (adjusted odds ratio, 0.45 [95% CI, 0.18–1.00], P=0.065) at the end of procedural digital subtraction angiography trended towards less adequate aneurysm occlusion on last follow-up.DiscussionThe WEB device, when evaluated in a large cohort of ruptured and unruptured aneurysms at any intracranial location, has an efficacy and safety profile that approximates currently available endovascular techniques.Our results emphasizes the importance of achieving optimal aneurysm occlusion after the initial treatment. To this end, oversizing of WEB device to ensure neck bridging has been recommended.2 Comparison of WEB versus other endovascular treatments are included in the Supplemental Material.Limitations of our study include the nonrandomized and retrospective nature of our study that predispose to selection and confirmation bias, the lack of a core laboratory, and the lack of uniformity in the radiological modalities used for follow-up imaging.Article InformationSources of FundingDr Stapleton was supported by the Andrew David Heitman Neurovascular Research Fund. Dr Dmytriw was supported by the Society of NeuroInterventional Surgery (SNIS) Foundation Young Investigator Research Grant Program. Dr Danilo Bengzon Diestro reports compensation from Medtronic for other services. Dr Cuellar-Saenz reports compensation from MicroVention, Inc for consultant services. Dr Möhlenbruyasuch reports compensation from Medtronic for consultant services and compensation from MicroVention, Inc for consultant services. Dr Vachhani reports compensation from MicroVention, Inc for consultant services. Dr Schirmer reports grants from Penumbra, Inc to other. Dr Starke reports grants from NIH Clinical Center; compensation from Arthur L. and Elaine V. Johnson Foundation for consultant services; grants from Medtronic USA, Inc; and compensation from Penumbra, Inc. for consultant services. Dr Puri reports compensation from Balt USA, LLC for consultant services; compensation from Medtronic for consultant services; compensation from Stryker for consultant services; compensation from MicroVention, Inc for consultant services; compensation from Johnson & Johnson Health Care Systems Inc for consultant services; and compensation from Merit Medical Systems Inc for consultant services. Dr Griessenauer reports compensation from MicroVention, Inc for consultant services; compensation from Stryker Corporation for consultant services; grants from Medtronic USA, Inc; and grants from Penumbra, Inc. Dr Asadi reports compensation from MicroVention, Inc for consultant services. Dr Siddiqui reports stock options in StimMed, LLC; stock holdings in Tulavi Therapeutics, Inc; stock holdings in Bend IT Technologies, Ltd; compensation from Medtronic Vascular, Inc for consultant services; stock holdings in Sense Diagnostics, Inc; stock holdings in Imperative Care, Inc; compensation from Penumbra, Inc. for consultant services; compensation from IRRAS USA, Inc for consultant services; securities holdings in SongBird Therapy; stock holdings in Neurotechnology Investors; compensation from Vassol for consultant services; stock options in Silk Road Medical, Inc.; stock holdings in Q?Apel Medical, Inc; stock options in Vizai, Inc; stock holdings in Instylla, Inc; compensation from Stryker Corporation for consultant services; compensation from MicroVention, Inc for consultant services; compensation from W. L. Gore & Associates, Inc for consultant services; stock holdings in Radical Catheter Technologies, Inc; securities holdings in Vastrax, LLC; stock holdings in NeuroRadial Technologies, Inc; compensation from Cardinal Health 200 LLC for consultant services; stock holdings in Truvic Medical, Inc.; stock options in CVAID Ltd; stock options in PerFlow Medical, Ltd; stock holdings in BlinkTBI, Inc; compensation from Apellis Pharmaceuticals, Inc for consultant services; securities holdings in Cognition Medical; compensation from Amnis Therapeutics for consultant services; compensation from Corindus Inc. for consultant services; securities holdings in Neurovascular Diagnostics; compensation from Minnetronix Neuro, Inc for consultant services; stock holdings in Viseon, Inc.; stock holdings in Synchron, Inc; stock holdings in Spinnaker Medical, Inc; compensation from Johnson & Johnson Medical Devices & Diagnostics Group—Latin America, L.L.C. for consultant services; stock options in Three Rivers Medical, Inc; compensation from Vizai, Inc for consultant services; stock holdings in Endostream Medical, Ltd; an ownership stake in Medtronic; stock holdings in Adona Medical, Inc; securities holdings in QAS.ai, Inc; compensation from BOSTON SCIENTIFIC CORPORATION for consultant services; stock options in Cerevatech Medical, Inc; securities holdings in VICIS, Inc; an ownership stake in Integra Lifesciences, Corp; securities holdings in Launch NY, Inc; stock holdings in Serenity Medical, Inc.; stock holdings in E8, Inc; stock holdings in Cerebrotech Medical Systems, Inc; and compensation from Canon Medical Systems USA, Inc for consultant services. Dr Ducruet reports compensation from Penumbra, Inc for data and safety monitoring services; compensation from Stryker for consultant services; compensation from cerenovus for consultant services; compensation from Medtronic for consultant services; and compensation from koswire for consultant services. Dr Aziz-Sultan reports compensation from MicroVention, Inc for other services. Dr Cognard reports compensation from MicroVention, Inc for consultant services. Dr Patel reports compensation from MicroVention, Inc. for consultant services; compensation from Medtronic for consultant services; and compensation from Penumbra, Inc for consultant services.DisclosuresNone.Supplemental MaterialSupplemental MethodsTables S1–S7Nonstandard Abbreviations and AcronymsWEBWoven EndoBridge deviceFootnotesSupplemental Material is available at https://www.ahajournals.org/doi/suppl/10.1161/STROKEAHA.121.037609.For Sources of Funding and Disclosures, see pages e48–e49.Correspondence to: Adam A. Dmytriw, MD, MPH, MSc, Neuroendovascular Program, Massachusetts General Hospital, Harvard Medical School, 55 Fruit St, Boston, MA 02114. Email [email protected]harvard.eduReferences1. Fiorella D, Arthur A, Byrne J, Pierot L, Molyneux A, Duckwiler G, McCarthy T, Strother C. Interobserver variability in the assessment of aneurysm occlusion with the WEB aneurysm embolization system.J Neurointerv Surg. 2015; 7:591–595. doi: 10.1136/neurintsurg-2014-011251Google Scholar2. Goyal N, Hoit D, DiNitto J, Elijovich L, Fiorella D, Pierot L, Lamin S, Spelle L, Saatci I, Cekirge S, et al.. How to WEB: a practical review of methodology for the use of the Woven EndoBridge.J Neurointerv Surg. 2020; 12:512–520. doi: 10.1136/neurintsurg-2019-015506Google Scholar Previous Back to top Next FiguresReferencesRelatedDetailsCited By Chen J, Mirshahi S, Jeelani Y, Bernstock J, Stapleton C and Patel N (2022) Delayed Rupture of an Anterior Communicating Artery Aneurysm After Elective Woven Endobridge Embolization, Re-Treated With Microsurgical Clipping: Operative Technique and Systematic Review, World Neurosurgery, 10.1016/j.wneu.2022.06.021, Online publication date: 1-Jun-2022. Hecker C, Broussalis E, Griessenauer C and Killer-Oberpfalzer M (2022) A mini-review of intrasaccular flow diverters, Journal of NeuroInterventional Surgery, 10.1136/neurintsurg-2021-018426, (neurintsurg-2021-018426) Related articlesCorrection to: International Study of Intracranial Aneurysm Treatment Using Woven EndoBridge: Results of the WorldWideWEB ConsortiumStroke. 2022;53:e128-e128 February 2022Vol 53, Issue 2Article InformationMetrics © 2021 American Heart Association, Inc.https://doi.org/10.1161/STROKEAHA.121.037609PMID: 34915737 Originally publishedDecember 17, 2021 Keywordsmiddle cerebral arterycomputed tomography angiographymagnetic resonance angiographyruptured aneurysmsintracranial aneurysmPDF download Advertisement SubjectsCerebral AneurysmIntracranial HemorrhageVascular Disease

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Intracranial Aneurysms: Treatment and Complications Cerebrovascular and Carotid Artery Diseases Moyamoya disease diagnosis and treatment

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Publication Details

Published in: Stroke

Volume 53, Issue 2, pp. e47-e49

DOI: 10.1161/strokeaha.121.037609

Field-Weighted Citation Impact: 2.94