HIV-1LAI Nef blocks the development of hematopoietic stem/progenitor cells into myeloid-erythroid lineage cells

20219 citationsJournal Articlegold Open Access

Authors

Wei Zou · Second Affiliated Hospital of Nanchang University

Juanjuan Xing · Nanchang University

Shijie Zou · Nanchang University

Mei Jiang · Nanchang University

Xinping Chen · Nanchang University

Qi Chen · Nanchang University

Daozheng Liu ·

Abstract

Our novel findings demonstrate LAI Nef compromised the development of myeloid-erythroid lineage cells, and therapeutics targeting Nef would be promising in correcting HIV-1 associated hematopoietic abnormalities.

Topics & Keywords

HIV Research and Treatment Immune Cell Function and Interaction T-cell and B-cell Immunology

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Biology Direct

Volume 16, Issue 1, pp. 27-27

DOI: 10.1186/s13062-021-00317-3

Field-Weighted Citation Impact: 1.29