Effects of Alirocumab on Triglyceride Metabolism: A Fat-Tolerance Test and Nuclear Magnetic Resonance Spectroscopy Study

20227 citationsJournal Articlegold Open Access

Authors

Thomas Metzner · Medical University of Graz

Deborah R. Leitner · Medical University of Graz

Karin Mellitzer · Medical University of Graz

Andrea Beck · Medical University of Graz

Harald Sourij · Medical University of Graz

Tatjana Stojaković

Gernot Reishofer · Medical University of Graz

Abstract

Significant effects of alirocumab on triglyceride metabolism were not detectable in the ALIROCKS trial. The total circulating PCSK9 concentration might be a useful biomarker to differentiate non-adherence from non-response to PCSK9 antibodies.

Topics & Keywords

Lipoproteins and Cardiovascular Health Atherosclerosis and Cardiovascular Diseases Systemic Lupus Erythematosus Research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Biomedicines

Volume 10, Issue 1, pp. 193-193

DOI: 10.3390/biomedicines10010193

Field-Weighted Citation Impact: 1.31