High or increasing serum NfL is predictive of impending multiple sclerosis relapses

202259 citationsJournal Articlehybrid Open Access

Authors

Simon Thebault · Ottawa Hospital Research Institute

Michael Reaume · Ottawa Hospital Research Institute

Ruth Ann Marrie · University of Manitoba

James Marriott · University of Manitoba

Roberto Furlan · Istituti di Ricovero e Cura a Carattere Scientifico

Alice Laroni · University of Genoa

Ronald A. Booth

Abstract

Canada:NCT02239393, Italy:NCT01854957&EudraCT, 2011-001295-19 CLASSIFICATION OF EVIDENCE: This study provides class 1 evidence that high baseline and longitudinal increases in sNfL are predictive of impending relapses in patients with active MS.

Topics & Keywords

Multiple Sclerosis Research Studies Amyotrophic Lateral Sclerosis Research Skin and Cellular Biology Research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Multiple Sclerosis and Related Disorders

Volume 59, pp. 103535-103535

DOI: 10.1016/j.msard.2022.103535

Field-Weighted Citation Impact: 8.01