Shortened Leukocyte Telomere Length Is Associated With Glycemic Progression in Type 2 Diabetes: A Prospective and Mendelian Randomization Analysis

202297 citationsJournal Articlebronze Open Access

Authors

Feifei Cheng · Chinese University of Hong Kong

Andrea O. Y. Luk · Chinese University of Hong Kong

Mai Shi · Chinese University of Hong Kong

Chuiguo Huang · Chinese University of Hong Kong

Guozhi Jiang · Sun Yat-sen University

Aimin Yang · Chinese University of Hong Kong

Hongjiang Wu

Abstract

Shorter rLTL was significantly associated with an increased risk of glycemic progression in individuals with type 2 diabetes, independent of established risk factors. Telomere length may be a useful biomarker for glycemic progression in people with type 2 diabetes.

Topics & Keywords

Telomeres, Telomerase, and Senescence Diabetes and associated disorders Adipose Tissue and Metabolism

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Diabetes Care

Volume 45, Issue 3, pp. 701-709

DOI: 10.2337/dc21-1609

Field-Weighted Citation Impact: 11.81