Intra‐articular injections of platelet‐rich plasma decrease pain and improve functional outcomes than sham saline in patients with knee osteoarthritis

In this randomized clinical trial of patients with KOA, P-PRP was superior to sham saline in treating KOA. P-PRP was effective for achieving at least 24 months of symptom relief and slowing the progress of KOA, with both P-PRP and saline being comparable in safety profiles.