Chemotherapy in advanced ovarian cancer: an overview of randomised clinical trials. Advanced Ovarian Cancer Trialists Group.

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Authors

Lesley Stewart · SWOG Cancer Research Network

Kristian Aabo · Eastern Cooperative Oncology Group

P I Adnitt · Gynecologic Oncology Group

Malcolm Adams · Gynecologic Oncology Group

Susanne Alberts · Australia New Zealand Gynaecological Oncology Group

V. Barley · SWOG Cancer Research Network

David Bell

Abstract

In the past, randomised clinical trials of chemotherapy in advanced ovarian cancer have been much too small to detect the degree of benefit which this overview suggests is realistic for currently available chemotherapeutic regimens. Hence a new trial comparing cisplatin, doxorubicin, and cyclophosphamide (CAP) with carboplatin has been launched and plans to accrue 2000 patients.

Topics & Keywords

Chemotherapy-induced organ toxicity mitigation Ovarian cancer diagnosis and treatment Chemotherapy-induced cardiotoxicity and mitigation

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: BMJ

Volume 303, Issue 6807, pp. 884-893

DOI: 10.1136/bmj.303.6807.884

Field-Weighted Citation Impact: 22.06