Genetic Associations and Architecture of Asthma-COPD Overlap

202242 citationsReviewhybrid Open Access

Authors

Catherine John · University of Leicester

Anna L. Guyatt · University of Leicester

Nick Shrine · University of Leicester

Richard Packer · University of Leicester

Thorunn A. Olafsdottir · deCODE Genetics (Iceland)

Jiangyuan Liu · Harvard University

Lystra P. Hayden ·

Abstract

We identified eight signals for asthma-COPD overlap, which may represent loci that predispose to type 2 inflammation, and serious long-term consequences of asthma.

Topics & Keywords

Asthma and respiratory diseases Chronic Obstructive Pulmonary Disease (COPD) Research Pediatric health and respiratory diseases

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: CHEST Journal

Volume 161, Issue 5, pp. 1155-1166

DOI: 10.1016/j.chest.2021.12.674

Field-Weighted Citation Impact: 4.95