Inflammation and Brain Structure in Schizophrenia and Other Neuropsychiatric Disorders

2022285 citationsJournal Articlehybrid Open Access

Authors

John A. Williams · Health Data Research UK

Stephen Burgess · MRC Biostatistics Unit

John Suckling · University of Cambridge

Paris Alexandros Lalousis · University of Birmingham

Fatima Batool · Medical Research Council

Siân Lowri Griffiths · University of Birmingham

Edward Palmer ·

Abstract

In this study, genetically determined IL-6 was associated with brain structure and potentially affects areas implicated in developmental neuropsychiatric disorders, including schizophrenia and autism.

Topics & Keywords

Tryptophan and brain disorders Neuroinflammation and Neurodegeneration Mechanisms Gut microbiota and health

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: JAMA Psychiatry

Volume 79, Issue 5, pp. 498-498

DOI: 10.1001/jamapsychiatry.2022.0407

Field-Weighted Citation Impact: 20.21