MIRO2 Regulates Prostate Cancer Cell Growth via GCN1-Dependent Stress Signaling

202222 citationsJournal Articlehybrid Open Access

Authors

Madison Furnish · University of Colorado Anschutz Medical Campus

Dillon P. Boulton · University of Colorado Anschutz Medical Campus

Victoria Genther · University of Colorado Anschutz Medical Campus

Denisa Grofova · University of Colorado Anschutz Medical Campus

Mitchell Lee Ellinwood · University of Colorado Anschutz Medical Campus

Lina Romero · University of Colorado Anschutz Medical Campus

Abstract

MIRO2/GCN1/GCN2 constitute a novel mitochondrial signaling pathway that controls androgen-independent and androgen-sensitive prostate cancer cell growth.

Topics & Keywords

Circular RNAs in diseases MicroRNA in disease regulation Endoplasmic Reticulum Stress and Disease

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Molecular Cancer Research

Volume 20, Issue 4, pp. 607-621

DOI: 10.1158/1541-7786.mcr-21-0374

Field-Weighted Citation Impact: 1.91