Artificial Intelligence–Powered Spatial Analysis of Tumor-Infiltrating Lymphocytes as Complementary Biomarker for Immune Checkpoint Inhibition in Non–Small-Cell Lung Cancer

2022267 citationsJournal Articlehybrid Open Access

Authors

Sehhoon Park · Samsung Medical Center

Chan‐Young Ock

Hyojin Kim · Seoul National University Bundang Hospital

Sérgio Pereira

Seonwook Park · Samsung Medical Center

Minuk Ma

Sangjoon Choi · Samsung Medical Center

Seokhwi Kim · Ajou University

Abstract

The AI-powered spatial analysis of TIL correlated with tumor response and progression-free survival of ICI in advanced NSCLC. This is potentially a supplementary biomarker to TPS as determined by a pathologist.

Topics & Keywords

Cancer Immunotherapy and Biomarkers Cancer Genomics and Diagnostics Immunotherapy and Immune Responses

Publication Details

Published in: Journal of Clinical Oncology

Volume 40, Issue 17, pp. 1916-1928

DOI: 10.1200/jco.21.02010

Field-Weighted Citation Impact: 26.58

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Artificial Intelligence–Powered Spatial Analysis of Tumor-Infiltrating Lymphocytes as Complementary Biomarker for Immune Checkpoint Inhibition in Non–Small-Cell Lung Cancer

Authors

Abstract

Topics & Keywords

Publication Details