Metagenomic Identification of Microbial Signatures Predicting Pancreatic Cancer From a Multinational Study

2022202 citationsJournal Articlehybrid Open Access

Authors

Naoyoshi Nagata · Tokyo Medical University

Suguru Nishijima · Waseda University

Yasushi Kojima · National Center for Global Health and Medicine

Yuya Hisada · National Center for Global Health and Medicine

Koh Imbe · National Center for Global Health and Medicine

Tohru Miyoshi‐Akiyama · National Center for Global Health and Medicine

Wataru Suda

Abstract

Metagenomics targeting the gut and oral microbiomes can provide a powerful source of biomarkers for identifying individuals with PDAC and their prognoses. The identification of shared gut microbial signatures for PDAC in Asian and European cohorts indicates the presence of robust and global gut microbial biomarkers.

Topics & Keywords

Pancreatic and Hepatic Oncology Research Gut microbiota and health Epigenetics and DNA Methylation

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Gastroenterology

Volume 163, Issue 1, pp. 222-238

DOI: 10.1053/j.gastro.2022.03.054

Field-Weighted Citation Impact: 20.82