Efficacy and Safety of Weekly Somatrogon vs Daily Somatropin in Children With Growth Hormone Deficiency: A Phase 3 Study

202293 citationsJournal Articlebronze Open Access

Authors

Cheri Deal · Université de Montréal

Joel Steelman · Cook Children's Medical Center

Elpis Vlachopapadopoulou · Panagiotis & Aglaia Kyriakou Children's Hospital

Renata Stawerska · Polish Mother’s Memorial Hospital Research Institute

Lawrence A. Silverman · Atlantic Health System

Moshe Phillip · Tel Aviv University

Ho-Seong Kim

Abstract

The efficacy of once-weekly somatrogon was noninferior to once-daily somatropin, with similar safety and tolerability profiles. (ClinicalTrials.gov no. NCT02968004).

Topics & Keywords

Growth Hormone and Insulin-like Growth Factors Sexual Differentiation and Disorders Birth, Development, and Health

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: The Journal of Clinical Endocrinology & Metabolism

Volume 107, Issue 7, pp. e2717-e2728

DOI: 10.1210/clinem/dgac220

Field-Weighted Citation Impact: 11.30