Comparative Effectiveness of Allopurinol and Febuxostat in Gout Management

202293 citationsJournal Articlegreen Open Access

Authors

James R. O’Dell · VA Nebraska Western Iowa Health Care System

Mary T. Brophy · VA Boston Healthcare System

Michael H. Pillinger · VA NY Harbor Healthcare System

Tuhina Neogi · Boston University

Paul M. Palevsky · University of Pittsburgh

Hongsheng Wu · Wentworth Institute of Technology

Anne Davis‐Karim

Abstract

Allopurinol and febuxostat achieved serum urate goals in patients with gout; allopurinol was noninferior to febuxostat in controlling flares. Similar outcomes were noted in participants with stage 3 chronic kidney disease. (Funded by the Cooperative Studies Program of the Department of Veterans Affairs Office of Research and Development; ClinicalTrials.gov identifier, NCT02579096.).

Topics & Keywords

Gout, Hyperuricemia, Uric Acid Case Reports on Hematomas Hepatitis C virus research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: NEJM Evidence

Volume 1, Issue 3

DOI: 10.1056/evidoa2100028

Field-Weighted Citation Impact: 12.39