Biocompatible poly(<i>N</i>-(ω-acryloyloxy-<i>n</i>-alkyl)-2-pyrrolidone)s with widely-tunable lower critical solution temperatures (LCSTs): a promising alternative to poly(<i>N</i>-isopropylacrylamide)

The biocompatible (co)polymers undergoes a thermal stimulus-driven liquid–liquid phase separation and form coacervates above the lower critical solution temperature (LCST). The LCSTs are able to be precisely controlled between 0 °C and 100 °C.