Clinicopathologic and Genomic Landscape of Non-Small Cell Lung Cancer Brain Metastases

202237 citationsJournal Articlegold Open Access

Authors

Richard S.P. Huang · Foundation Medicine (United States)

Lukas Harries · Foundation Medicine (United States)

Brennan Decker · Foundation Medicine (United States)

Matthew Hiemenz · Foundation Medicine (United States)

Karthikeyan Murugesan · Foundation Medicine (United States)

James Creeden · Foundation Medicine (United States)

Khaled Tolba

Abstract

Herein, we defined the clinicopathologic, genomic, and biomarker landscape of a large cohort of patients with NSCLC-BM which can help inform study design of future clinical studies for patients with NSCLC with BM. In certain clinical situations, metastatic NSCLC brain tissue or cerebral spinal fluid specimens may be needed to fully optimize personalized treatment.

Topics & Keywords

Lung Cancer Treatments and Mutations Lung Cancer Research Studies Brain Metastases and Treatment

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: The Oncologist

Volume 27, Issue 10, pp. 839-848

DOI: 10.1093/oncolo/oyac094

Field-Weighted Citation Impact: 5.32