Small Extracellular Vesicles From Brown Adipose Tissue Mediate Exercise Cardioprotection

2022126 citationsJournal Article

Authors

Hang Zhao · Pingjin Hospital

Xiyao Chen · Air Force Medical University

Yunlong Xia · Xijing Hospital

Abstract

The sEVs secreted by BAT participate in exercise cardioprotection via delivering the cardioprotective miRNAs into the heart. These results provide novel insights into the mechanisms underlying the BAT-cardiomyocyte interaction and highlight BAT sEVs and their contained miRNAs as alternative candidates for exercise cardioprotection.

Topics & Keywords

Adipose Tissue and Metabolism Extracellular vesicles in disease Cardiovascular Disease and Adiposity

Publication Details

Published in: Circulation Research

Volume 130, Issue 10, pp. 1490-1506

DOI: 10.1161/circresaha.121.320458

Field-Weighted Citation Impact: 13.80

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Small Extracellular Vesicles From Brown Adipose Tissue Mediate Exercise Cardioprotection

Authors

Abstract

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Publication Details