Comparison of Open and Transnasal Endoscopic Approaches to the Skull Base in the Endoscopic Skull Base Era

Introduction: Selection bias cannot be overemphasized when comparing endoscopic and open skull base series. However, skull base surgery is a rapidly changing field, and it remains imperative to describe the differences in complication rates as the endoscopic approach is utilized for increasingly complex disease and the open approach becomes reserved for the most extensive disease.