Pramipexole vs Levodopa as Initial Treatment for Parkinson Disease

2000760 citationsJournal Article

Authors

Abstract

Fewer patients receiving initial treatment for PD with pramipexole developed dopaminergic motor complications than with levodopa therapy. Despite supplementation with open-label levodopa in both groups, the levodopa-treated group had a greater improvement in total UPDRS compared with the pramipexole group. JAMA. 2000;284:1931-1938.

Topics & Keywords

Parkinson's Disease Mechanisms and Treatments Neurological disorders and treatments Parkinson's Disease and Spinal Disorders

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: JAMA

Volume 284, Issue 15, pp. 1931-1931

DOI: 10.1001/jama.284.15.1931

Field-Weighted Citation Impact: 30.05