Technical validation of an autoantibody test for lung cancer

201086 citationsJournal Articlehybrid Open Access

Authors

Alan Murray

Caroline Chapman · Nottingham City Hospital

Graham Healey

Laura J. Peek · OncoImmune (United States)

Grace F. Parsons · Parsons (United States)

David Baldwin · Nottingham City Hospital

A. Barnes · OncoImmune (United States)

Herb F. Sewell

Abstract

A calibrated six-panel assay of TAAs has been validated for identifying nearly 40% of primary lung cancers via a peripheral blood test. Levels of reproducibility, precision and linearity would be acceptable for an assay used in a regulated clinical setting.

Topics & Keywords

Monoclonal and Polyclonal Antibodies Research Immunotherapy and Immune Responses T-cell and B-cell Immunology

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Annals of Oncology

Volume 21, Issue 8, pp. 1687-1693

DOI: 10.1093/annonc/mdp606

Field-Weighted Citation Impact: 3.98