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Engineered CRISPR-Cas9 nucleases with altered PAM specificities

20151,649 citationsJournal Articlegreen Open Access

Authors

Benjamin P. Kleinstiver · Massachusetts General Hospital

Michelle S. Prew · Massachusetts General Hospital

Shengdar Q. Tsai · Massachusetts General Hospital

Ved V. Topkar · Massachusetts General Hospital

Nathalie T. Nguyen · Massachusetts General Hospital

Zongli Zheng · Center for Cancer Research

Andrew P. W. Gonzales

Topics & Keywords

CRISPR and Genetic Engineering Advanced biosensing and bioanalysis techniques Mosquito-borne diseases and control

UN Sustainable Development Goals

Life in Land

Publication Details

Published in: Nature

Volume 523, Issue 7561, pp. 481-485

DOI: 10.1038/nature14592

Field-Weighted Citation Impact: 87.22

Engineered CRISPR-Cas9 nucleases with altered PAM specificities | Researchclopedia

· Massachusetts General Hospital

Zhuyun Li · Massachusetts General Hospital

Randall T. Peterson · Massachusetts General Hospital

Jing-Ruey Joanna Yeh · Massachusetts General Hospital

Martin J. Aryee · Harvard University

J. Keith Joung · Massachusetts General Hospital