Structure and function of thrombomodulin: a natural anticoagulant

NDOTHELIAL CELLS lining blood vessels possess E anticoagulant functions, although they can rapidly become procoagulant when injured. The anticoagulant actions include production of prostacyclin,' secretion of plasminogen activator,* cell surface heparin containing proteoglycans that stimulate certain coagulation factor inhibitor^,^