Host methylation predicts SARS-CoV-2 infection and clinical outcome

202178 citationsJournal Articlegold Open Access

Authors

Iain R. Konigsberg · University of Colorado Anschutz Medical Campus

Bret Barnes · Illumina (United States)

Monica Campbell · University of Colorado Anschutz Medical Campus

Elizabeth Davidson · University of Colorado Anschutz Medical Campus

Yingfei Zhen · University of Colorado Anschutz Medical Campus

Olivia Pallisard · University of Colorado Anschutz Medical Campus

Meher P. Boorgula

Abstract

In summary, the strong COVID-19-specific epigenetic signature in peripheral blood driven by key immune-related pathways related to infection status, disease severity, and clinical deterioration provides insights useful for diagnosis and prognosis of patients with viral infections.

Topics & Keywords

Epigenetics and DNA Methylation Immune responses and vaccinations Gut microbiota and health

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Communications Medicine

Volume 1, Issue 1, pp. 42-42

DOI: 10.1038/s43856-021-00042-y

Field-Weighted Citation Impact: 5.52