Soluble HLA peptidome of pleural effusions is a valuable source for tumor antigens

20227 citationsJournal Articlegold Open Access

Authors

Sofia Khazan-Kost · Technion – Israel Institute of Technology

Gal Cafri · Sheba Medical Center

Dganit Melamed Kadosh · Technion – Israel Institute of Technology

Navit Mooshayef · Sheba Medical Center

Sumit Chatterji · Sheba Medical Center

Dan Dominissini · Sheba Medical Center

Sigal Manor

Abstract

Pleural effusions contain sHLA-peptide complexes, and the pleural effusion HLA peptidome of patients with malignant tumors can serve as a rich source of biomarkers for tumor diagnosis and potential candidates for personalized immunotherapy.

Topics & Keywords

vaccines and immunoinformatics approaches Peptidase Inhibition and Analysis Immunotherapy and Immune Responses

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal for ImmunoTherapy of Cancer

Volume 10, Issue 5, pp. e003733-e003733

DOI: 10.1136/jitc-2021-003733

Field-Weighted Citation Impact: 0.61