Stunting Status and Exposure to Infection and Inflammation in Early Life Shape Antibacterial Immune Cell Function Among Zimbabwean Children

202234 citationsJournal Articlegold Open Access

Authors

Kuda Mutasa · Zvitambo Institute for Maternal and Child Health Research

Joice Tome · Zvitambo Institute for Maternal and Child Health Research

Sandra Rukobo · Zvitambo Institute for Maternal and Child Health Research

Margaret Govha · Zvitambo Institute for Maternal and Child Health Research

Patience Mushayanembwa · Zvitambo Institute for Maternal and Child Health Research

Farai S. Matimba · Zvitambo Institute for Maternal and Child Health Research

Abstract

Antibacterial immune function among 18-month-old children in a low-income setting was shaped by their stunting status and prior exposure to maternal inflammation and household WASH. Heterogeneity in immune function due to adverse exposures in early life could plausibly contribute to infection susceptibility.

Topics & Keywords

Child Nutrition and Water Access Global Maternal and Child Health Poverty, Education, and Child Welfare

UN Sustainable Development Goals

Zero hunger

Publication Details

Published in: Frontiers in Immunology

Volume 13, pp. 899296-899296

DOI: 10.3389/fimmu.2022.899296

Field-Weighted Citation Impact: 3.60