Effects of Previous Infection and Vaccination on Symptomatic Omicron Infections

2022567 citationsJournal Articlebronze Open Access

Authors

Heba Altarawneh · Center for Global Health

Hiam Chemaitelly · Center for Global Health

Houssein H. Ayoub · Center for Global Health

Patrick Tang · Center for Global Health

Mohammad R. Hasan · Center for Global Health

Hadi M. Yassine · Center for Global Health

Hebah A. Al-Khatib

Abstract

No discernable differences in protection against symptomatic BA.1 and BA.2 infection were seen with previous infection, vaccination, and hybrid immunity. Vaccination enhanced protection among persons who had had a previous infection. Hybrid immunity resulting from previous infection and recent booster vaccination conferred the strongest protection. (Funded by Weill Cornell Medicine-Qatar and others.).

Topics & Keywords

SARS-CoV-2 and COVID-19 Research COVID-19 Clinical Research Studies SARS-CoV-2 detection and testing

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 387, Issue 1, pp. 21-34

DOI: 10.1056/nejmoa2203965

Field-Weighted Citation Impact: 56.38