The role of epigenetic modifications in drug resistance and treatment of breast cancer

2022129 citationsReviewgold Open Access

Authors

Mohsen Karami Fath · Kharazmi University

Ali Azargoonjahromi · Shiraz University of Medical Sciences

Arash Kiani · Yasuj University of Medical Sciences

Fateme Jalalifar · University of Jiroft

Parisa Osati · University of Tehran

Mahsa Akbari Oryani · Mashhad University of Medical Sciences

Fateh Shakeri

Abstract

Herein we discuss the molecular and epigenetic mechanisms underlying breast cancer progression and resistance as well as various aspects of epigenetic-based therapies as monotherapy and combined with immunotherapy.

Topics & Keywords

Epigenetics and DNA Methylation Histone Deacetylase Inhibitors Research Advanced Breast Cancer Therapies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Cellular & Molecular Biology Letters

Volume 27, Issue 1, pp. 52-52

DOI: 10.1186/s11658-022-00344-6

Field-Weighted Citation Impact: 10.83