Synovial Inflammatory Pathways Characterize <scp>Anti‐TNF</scp>–Responsive Rheumatoid Arthritis Patients

Collectively, these data suggest that RA patients with robust responses to anti-TNF therapies are characterized at baseline by immune pathway activation, which decreases following anti-TNF treatment. Understanding mechanisms that define patient responsiveness to anti-TNF treatment may assist in development of predictive markers of patient response and earlier treatment options.